Extracellular vesicles of the blood-brain barrier
نویسندگان
چکیده
منابع مشابه
Extracellular vesicles of the blood-brain barrier
Extracellular vesicles (ECV), like exosomes, gained recently a lot of attention as potentially playing a significant role in neurodegenerative diseases, particularly in Aβ pathology. While there are a lot of reports on ECV/exosomes derived from a variety of cell types, there is limited information on ECV/exosomes originated from brain microvascular endothelial cells forming the blood-brain barr...
متن کاملBrain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrier
Brain metastasis is an important cause of mortality in breast cancer patients. A key event during brain metastasis is the migration of cancer cells through blood-brain barrier (BBB). However, the molecular mechanism behind the passage through this natural barrier remains unclear. Here we show that cancer-derived extracellular vesicles (EVs), mediators of cell-cell communication via delivery of ...
متن کاملP45: The Role of Blood-Brain Barrier Breakdown Following Traumatic Brain in Post-Traumatic Epilepsy
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملP 150: The Role of Blood Brain Barrier Restoration in the Multiple Sclerosis
Blood Brain Barrier (BBB) is a specialized non fenestrate barrier that formation by the endothelial cells and controls the transportation of the cells and molecules in to the brain. Reducing in function of BBB is one of disruptions in neurological diseases like multiple sclerosis. Endothelial progenitor cell (EPC) help to the BBB to control the diapedesis of inflammatory cells & molecules in to...
متن کاملThe blood-brain barrier.
In autoimmune neurologic disorders, the blood-brain barrier (BBB) plays a central role in immunopathogenesis, since this vascular interface is an entry path for cells and effector molecules of the peripheral immune system to reach the target organ, the central nervous system (CNS). The BBB's unique anatomic structure and the tightly regulated interplay of its cellular and acellular components a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Tissue Barriers
سال: 2015
ISSN: 2168-8370
DOI: 10.1080/21688370.2015.1131804